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Dr. Medina-Franco's research focuses on computer-aided drug design. The research group conducts virtual screening of large compound databases to identify novel compounds directed to targets associated with the treatment of cancer, HIV/AIDS and other diseases. Molecular modeling and chemoinformatic methods are used for the structure-based and ligand-based optimization of bioactive compounds. The group also performs structural classification, diversity analysis and data mining of chemical libraries. Current projects include:
Research is conducted in a multidisciplinary environment with close collaborations with experimental research groups.
Dr. Jose Luis Medina-Franco received a Bachelor of Science in chemistry from the National Autonomous University of Mexico (UNAM) in 1998 and that same year, he joined Procter & Gamble in Mexico City, working in the research and development department. He received a Masters in Science in 2002 ("Synthesis of pyridinone-2(1H)-ones as precursors of potential HIV-1 Reverse Transcriptase Inhibitors") and a Ph.D. degree in 2005 ("Computer-Aided Drug Design. HIV-1 Reverse Transcriptase Inhibitors, Hypocholesterolemic and Antiparasitic Compounds"), both in Chemisty from UNAM, working in the laboratory of Professor Rafael Castillo. During his doctoral studies, Dr. Medina-Franco participated in research visits with Professor Jesus Jimenez-Barbero, in Madrid, Spain; Professor Alexander Tropsha at the University of North Carolina at Chapel Hill and Professor Gerald M. Maggiora at the University of Arizona. In 2005, he joined Professor Maggiora as a postdoctoral fellow. In August 2007, Dr. Medina-Franco was named Assistant Member at the Torrey Pines Institute for Molecular Studies in Florida.
2005 - Doctor of Philosophy (Chemistry): National Autonomous University of Mexico (UNAM), Mexico City, Mexico
2002 - Master of Science (Chemistry): National Autonomous University of Mexico (UNAM), Mexico City, Mexico
1998 - Bachelor of Science (Chemistry): National Autonomous University of Mexico (UNAM), Mexico City, Mexico
2007 - Present: Assistant Member, Torrey Pines Institute for Molecular Studies, Port St Lucie, Florida
2005 - 2007: Postdoctoral Fellow, University of Arizona, Tucson, Arizona
1998 - 2000: Senior Research Associate, Procter & Gamble, Mexico City, Mexico
Honors and Awards