Despite numerous attempts
and clinical trials, cancer vaccines in humans have
not proven to be effective. The reason for this is a
simple one: humans do not react immunologically to their
own body proteins, and most tumor proteins -- these
would be the key components of a cancer vaccine -- are
normal body proteins produced in abnormal amounts. In
short, they are ineffective because they do not provoke
strong immune responses.
To solve this problem, TPIMS' vast combinatorial
peptide libraries mimic tumor protein fragments that,
when tested as vaccines, provoke far stronger immune
responses capable of curing cancer in experimental
systems.
This proprietary technology is applied to the human
condition and is especially useful for the treatment
of prostate, breast, lung cancers and melanoma. This
program is highly effective in identifying the key
components of cancer vaccines over relatively short
periods of time.
The potential outcomes of this research program in
terms of human health and economics are enormous.
Dr. Wilson's
laboratory is conducting this research.
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